Dr. Courtney Kurtyka successfully defended her dissertation on August 1, 2014. Dr. Kurtyka has joined the lab of Dr. Melvin L. DePamphilis, Section Chief and member of the Senior Biomedical Research Service, National Institute of Child Health and Human Development.
Pictured from left to right: Committee members Jin Q. Cheng and Srikumar Chellappan; Major Professor Doug Cress; Courtney; Defense Chair Brian Law from the University of Florida; Committee member Eric Haura.
Dr. Kurtyka's publication record while in the Program:
E2F inhibition synergizes with paclitaxel in lung cancer cell lines. Kurtyka CA, Chen L, Cress WD. PLoS One. 2014 May 15;9(5):e96357. doi: 10.1371/journal.pone.0096357. eCollection 2014. PMID:24831239
IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer. Guo J, Kim D, Gao J, Kurtyka C, Chen H, Yu C, Wu D, Mittal A, Beg AA, Chellappan SP, Haura EB, Cheng JQ. Oncogene. 2013 Jan 10;32(2):151-9. doi: 10.1038/onc.2012.39. Epub 2012 Feb 13. PMID: 22330135
Tripartite motif containing 28 (Trim28) can regulate cell proliferation by bridging HDAC1/E2F interactions. Chen L, Chen DT, Kurtyka C, Rawal B, Fulp WJ, Haura EB, Cress WD .J Biol Chem. 2012 Nov 23;287(48):40106-18. doi: 10.1074/jbc.M112.380865. Epub 2012 Oct 11. PMID:23060449
A small-molecule E2F inhibitor blocks growth in a melanoma culture model. Ma Y, Kurtyka CA, Boyapalle S, Sung SS, Lawrence H, Guida W, Cress WD. Cancer Res. 2008 Aug 1;68(15):6292-9. doi: 10.1158/0008-5472.CAN-08-0121. PMID:18676853