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Cynthia  LeBron

Cynthia LeBron

Cynthia LeBron

  

Bio

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Cancer Biology's third graduate (May 2007), Dr. Cynthia LeBron received offers from Georgetown, Yale and Johns Hopkins. Following a two year postdoc in the laboratory of Dr. David Sidransky at Johns Hopkins University, Cindy joined Amgen as a Senior Regional MSL; she recently moved to Seattle Genetics as a Senior MSL . Dr. LeBron received the 2006 Best Overall Graduate Student Presentation award during USF Health Research Day.

Dr. LeBron's publication record while in the Program:

Eason DD, LeBron C, Coppola D, Moscinski LC, Livingston S, Sutton ET, Blanck G.  Development of CD30+ lymphoproliferative disease in mice lacking interferon regulatory factor-1.  Oncogene.  2003 Sep 18;22(40):6166-76.

LeBron C, Chen L, Gilkes D, Chen J.  Regulation of MDMX nuclear import and degradation by Chk2 and 14-3-3.  EMBO Journal . 25: 1196-1206. (2006)

Dr. LeBron's publication record since graduation:

Kim MS, Lebron C, Nagpal JK, Chae YK, Chang X, Huang Y, Chuang T, Yamashita K, Trink B, Ratovitski EA, Califano JA, Sidransky D.Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer.Biochem Biophys Res Commun. 2008 May 23;370(1):38-43. Epub 2008 Mar 17.

Kim MS, Chang X, LeBron C, Nagpal JK, Lee J, Huang Y, Yamashita K, Trink B, Ratovitski EA, Sidransky D. Neurofilament heavy polypeptide regulates the Akt-beta-catenin pathway in human esophageal squamous cell carcinoma. PLoS One. 2010 Feb 3;5(2):e9003.

Zou GM, Lebron C, Fu Y. RNAi knockdown of redox signaling protein Ape1 in the differentiation of mouse embryonic stem cells. Methods Mol Biol. 2010;650:121-8.

Guerrero-Preston R, Goldman LR, Brebi-Mieville P, Ili-Gangas C, Lebron C, Witter FR, Apelberg BJ, Hernández-Roystacher M, Jaffe A, Halden RU, Sidransky D. Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds. Epigenetics. 2010 Aug 16;5(6):539-46. Epub 2010 Aug 16. PMID: 20523118

LeBron C, Pal P, Brait M, Dasgupta S, Guerrero-Preston R, Looijenga LH, Kowalski J, Netto G, Hoque MO. Genome-wide analysis of genetic alterations in testicular primary seminoma using high resolution single nucleotide polymorphism arrays. Genomics. 2011 Jun;97(6):341-9. doi: 10.1016/j.ygeno.2011.02.011. Epub 2011 Mar 2. PMID: 21376111

Brait M, Munari E, LeBron C, Noordhuis MG, Begum S, Michailidi C, Gonzalez-Roibon N, Maldonado L, Sen T, Guerrero-Preston R, Cope L, Parrella P, Fazio VM, Ha PK, Netto GJ, Sidransky D, Hoque MO. Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma. Cell Cycle.3 Apr 1;12(7):1058-70. doi: 10.4161/cc.24050. Epub 2013 Feb 22. PMID: 23435205

Kagohara LT, Schussel JL, Subbannayya T, Sahasrabuddhe N, Lebron C, Brait M, Maldonado L, Valle BL, Pirini F, Jahuira M, Lopez J, Letelier P, Brebi-Mieville P, Ili C, Pandey A, Chatterjee A, Sidransky D, Guerrero-Preston R. Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile. Future Oncol. 2015;11(2):233-49. doi: 10.2217/fon.14.165. Epub 2014 Jul 28. PMID: 25066711