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Courtney  Schaal

Courtney Schaal

Courtney Schaal

  

Bio

Dr. Courtney Schaal, shown at Fall 2016 Commencement with her Major Professor Dr. Srikumar Chellappan, successfully defended her dissertation July 29, 2016. Dr. Schaal initially left for her postdoc at UNC Chapel Hill but returned for graduation. Dr. Schaal has the distinction of being the 50th graduate from the Cancer Biology PhD Program! Dr. Schaal works with a collaborative team of researchers at UNC Chapel Hill consisting of Brian Strahl, Ian Davis and Samantha Pattenden.

Dr. Schaal's publication record while in the Program:

Schaal, C. and Chellappan, S. Nicotine-mediated regulation of nicotinic-acetylcholine receptors in non-small cell lung adenocarcinoma by E2F1 and STAT1 transcription factors. PLOS One. 2016 May 26; 11(5):e0156451. PMID: 27228072

Schaal, C., Padmanabhan, J., and Chellappan, S. The role of nAChR and calcium signaling in pancreatic cancer initiation and progression. Cancers (Basel). 2015 Jul 31;7(3):1447-71. doi: 10.3390/cancers7030845. Review. PMID: 26264026

Bora-Singhal N, Nguyen J, Schaal C, Perumal D, Singh S, Coppola D, Chellappan S. YAP1 Regulates OCT4 Activity and SOX2 Expression to Facilitate self-renewal and Vascular Mimicry of Stem-like Cells. Stem Cells. 2015 June;33(6):1705-18.. doi: 10.1002/stem.1993.PMID:25754111

Perumal D, Pillai S, Nguyen J, Schaal C, Coppola D, Chellappan SP. Nicotinic acetylcholine receptors induce c-Kit ligand/Stem Cell Factor and promote stemness in an ARRB1/ ß-arrestin-1 dependent manner in NSCLC. Oncotarget. 2014 Nov 15;5(21):10486-502. PMID:25401222

Rizwani W, Schaal C, Kunigal S, Coppola D, Chellappan S. Mammalian lysine histone demethylase KDM2A regulates E2F1-mediated gene transcription in breast cancer cells. PLoS One. 2014 Jul 16;9(7):e100888. doi: 10.1371/journal.pone.0100888. eCollection 2014.PMID:25029110

Schaal C, Pillai S, Chellappan SP. The Rb-E2F Transcriptional Regulatory Pathway in Tumor Angiogenesis and Metastasis. Adv Cancer Res. 2014;121:147-82. doi: 10.1016/B978-0-12-800249-0.00004-4. PMID:24889531

Schaal C, Chellappan SP. Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers. Mol Cancer Res. 2014 Jan;12(1):14-23. doi: 10.1158/1541-7786.MCR-13-0541. Review. PMID:24398389