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Ildefonso  Vicente-Suarez

Ildefonso Vicente-Suarez

Ildefonso Vicente-Suarez

  

Bio

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Dr. Ildefonso Vicente-Suarez, pictured with one of his committee members, Dr. Julie Djeu, successfully defended his disseration on October 24, 2007. Dr. Vicente-Suarez has joined the lab of Dr. Hilde Cheroutre, La Jolla Institute of Allergy and Immunology, UCSD. Following his postdoc, Dr. Vicente-Suarez accepted a Scientist III position with Alkermes, a global biopharmaceutical company developing medicine for the treatment of central nervous systems diseases.

Dr. Vicente-Suarez's publication record while in the Program:

Vicente-Suarez I, Takahashi Y, Cheng F, Horna P, Wang HW, Wang HG, Sotomayor EM.Identification of a novel negative role of flagellin in regulating IL-10 production.Eur J Immunol. 2007 Nov;37(11):3164-75.

Dr. Vicente-Suarez's publication record since graduation:

Villagra A, Cheng F, Wang HW, Suarez I, Glozak M, Maurin M, Nguyen D, Wright KL, Atadja PW, Bhalla K, Pinilla-Ibarz J, Seto E, Sotomayor EM. The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance. Nature Immunology. November 16, 2009.

Vicente-Suarez I, Brayer J, Villagra A, Cheng F, Sotomayor EM. TLR5 ligation by flagellin converts tolerogenic dendritic cells into activating antigen-presenting cells that preferentially induce T-helper 1 responses. Immunol Lett. 2009 Aug 15;125(2):114-8.

Brayer J, Cheng F, Wang H, Horna P, Vicente-Suarez I, Pinilla-Ibarz J, Sotomayor EM. Enhanced CD8 T cell cross-presentation by macrophages with targeted disruption of STAT3. Immunol Lett. 2010 Jul 8;131(2):126-30.

Wang H, Cheng F, Woan K, Sahakian E, Merino O, Rock-Klotz J, Vicente-Suarez I, Pinilla-Ibarz J, Wright KL, Seto E, Bhalla K, Villagra A, Sotomayor EM. Histone deacetylase inhibitor LAQ824 augments inflammatory responses in macrophages through transcriptional regulation of IL-10. J Immunol. 2011 Apr 1;186(7):3986-96.

Vicente-Suarez I, Villagra A, Sotomayor EM. Signaling pathways in antigen presenting cells involved in the induction of T cell tolerance. As part of the monograph “Mechanisms of Tumor Immune Suppression. Springer Science and Business Media (in press).

Guma M, Stepniak D, Shaked H, Spehlmann ME, Shenouda S, Cheroutre H, Vicente-Suarez I, Eckmann L, Kagnoff MF, Karin M. Constitutive intestinal NF-?B does not trigger destructive inflammation unless accompanied by MAPK activation.J Exp Med. 2011 Aug 29;208(9):1889-900.

Vicente-Suarez I, Larange A, Reardon C, Matho M, Feau S, Chodaczek G, Park Y, Obata Y, Gold R, Wang-Zhu Y, Lena C, Zajonc DM, Schoenberger SP, Kronenberg M, Cheroutre H. Unique lamina propria stromal cells imprint the functional phenotype of mucosal dendritic cells. Mucosal Immunol. 2015 Jan;8(1):141-51. PMID: 24938743

Garcia-Carbonell R, Divakaruni AS, Lodi A, Vicente-Suarez I, Saha A, Cheroutre H, Boss GR, Tiziani S, Murphy AN, Guma M. Critical role of fibroblast-like synoviocytes glycolytic metabolism in rheumatoid arthritis. Arthritis Rheumatol. 2016 Jan 27. doi: 10.1002/art.39608. [Epub ahead of print] PMID: 26815411