Pictured above with her committee, Dr. Neha Kabra successfully defended her dissertation on March 4, 2010. From left to right: Major Professor Jiandong Chen, external chair James Manfredi from Mount Sinai School of Medicine, Neha, committee members Alvaro Monteiro, Doug Cress and Ken Wright. Dr. Kabra is now a Research Administrative Specialist at the University of Nebraska Medical Center.
Dr. Kabra's publication record while in the Program:
Kabra N, Li Z, Chen L, Li B, Zhang X, Wang C, Yeatman T, Coppola D, Chen J. SirT1 is an inhibitor of proliferation and tumor formation in colon cancer. J Biol Chem.. 2009 Jul 3;284(27):18210-7.
Kabra N, Wang C, Fang J, Chen J. Inhibition of SUB39H1 methyltransferase activity by DBC1 J Biol Chem. 2009 Apr 17;284(16):10361-6.
Chen L, Hou X, Li A, Kabra N, Ma Y, Nemoto S, Finkel T, Gu W, Cress WD, Chen J. Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage Nat Cell Biol.. 2006 Sep;8(9):1025-31.
Dr. Kabra's publication record following graduation:
Woods N, Trevino J, Coppola D, Chellappan S, Yang S, Padmanabhan J. Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and ß-catenin signaling. Oncotarget. 2015 Nov 3;6(34):35931-48. PMID: 26440150
Neha Kabra Woods and Jaya Padmanabhan. Inhibition of amyloid precursor protein processing enhances gemcitabine-mediated cytotoxicity in pancreatic cancer cells. Accepted in J Biol Chem.. 2013 Sept 10.
Yang L, Song T, Chen L, Kabra N, Zhen H, Koomen J, Seto E, Chen J. Regulation of SIRT1-NML binding by rRNA coordinates ribosome biogenesis with nutrient availability. Mol Cell Biol.. 2013 Oct; 33(19): 3835-48.
Song T, Yang L, Kabra N, Chen L, Koomen J, Haura EB, Chen J. The NAD+ synthesis enzyme Nicotinamide Mononucleotide Adenylytransferase (NMNAT1) regulates ribosomal RNA transcription. J Biol Chem.. 2013 Jul 19; 288(29):20908-17.
Neha Kabra Woods and Jaya Padmanabhan. Neuronal Calcium Signaling and Alzheimer's Disease. Adv Exp Med Biol.. 2012;740:1193-217.