The program’s second graduate (May 2005), Dr. Yu Pan, joined the laboratory of Dr. W. Stratford May, then director of the Shands Cancer Center, Gainesville, Florida. She then became a dental student in Minnesota and today is a board certified orthodontist in private practice.
Dr. Pan’s publication record while in the Program:
Chen L, Gilkes DM, Pan Y, Lane WS, Chen J. ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage. EMBO J. 2005 Oct 5;24(19):3411-22. Epub 2005 Sep 15.
Pan Y, Chen J. Modification of MDMX by sumoylation. Biochem Biophys Res Commun. 2005 Jul 8;3323(3):702-9.
Chen L, Li C, Pan Y, Chen J. Regulation of p53-MDMX interaction by casein kinase 1 alpha. Mol Cell Biol. 2005 Aug;25(15):6509-20.
Pan Y, Chen J. MDM2 promotes ubiquitination and degradation of MDMX. Mol Cell Bio. 2003 Aug;23(15):5113-21.
Gilkes DM, Pan Y, Coppola D, Yeatman T, Reuther GW, Chen J. Regulation of MDMX expression by mitogenic signaling. Mol Cell Biol. 2008 Mar;28(6):1999-2010. Epub 2008 Jan 2.
Publications since graduation:
Bennett RL, Blalock WL, Abtahi AM, Pan Y, Moyer SA, May WS. RAX, the PKR Activator sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy and viral infection. Blood. 2006 Aug 1;108(3):821-9.
Bennett RL, Pan Y, Christian J, Hui T, May WS Jr. The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G1 arrest. Cell Cycle. 2012 Jan 15;11(2):407-17. doi: 10.4161/cc.11.2.18999. Epub 2012 Jan 15. PMID: 22214662