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Yu  Pan

Yu Pan

Yu Pan

  

Bio

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The program’s second graduate (May 2005), Dr. Yu Pan, joined the laboratory of Dr. W. Stratford May, then director of the Shands Cancer Center, Gainesville, Florida. She then became a dental student in Minnesota and today is a board certified orthodontist in private practice.

Dr. Pan’s publication record while in the Program:

Chen L, Gilkes DM, Pan Y, Lane WS, Chen J.  ATM and Chk2-dependent phosphorylation of MDMX contribute to p53 activation after DNA damage.  EMBO J.  2005 Oct 5;24(19):3411-22.  Epub 2005 Sep 15.

Pan Y, Chen J.  Modification of MDMX by sumoylation.  Biochem Biophys Res Commun. 2005 Jul 8;3323(3):702-9.

Chen L, Li C, Pan Y, Chen J.  Regulation of p53-MDMX interaction by casein kinase 1 alpha.  Mol Cell Biol.  2005 Aug;25(15):6509-20.

Pan Y, Chen J.  MDM2 promotes ubiquitination and degradation of MDMX.  Mol Cell Bio.  2003 Aug;23(15):5113-21.

Gilkes DM, Pan Y, Coppola D, Yeatman T, Reuther GW, Chen J. Regulation of MDMX expression by mitogenic signaling. Mol Cell Biol. 2008 Mar;28(6):1999-2010. Epub 2008 Jan 2.

Publications since graduation:

Bennett RL, Blalock WL, Abtahi AM, Pan Y, Moyer SA, May WS. RAX, the PKR Activator sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy and viral infection. Blood. 2006 Aug 1;108(3):821-9.

Bennett RL, Pan Y, Christian J, Hui T, May WS Jr. The RAX/PACT-PKR stress response pathway promotes p53 sumoylation and activation, leading to G1 arrest. Cell Cycle. 2012 Jan 15;11(2):407-17. doi: 10.4161/cc.11.2.18999. Epub 2012 Jan 15. PMID: 22214662