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Wenlong  Bai

Wenlong Bai

Wenlong Bai
Professor

Contact

Office:
Phone: 813/974-0563
Email: wbai@health.usf.edu

Education

Ph.D., University of Texas M. D. Anderson Cancer Center, 1992
Postdoctoral Fellowship, Baylor College of Medicine at Texas Medical Center, 1992-1997

Research

Research in the laboratory focuses on the role of steroid hormone and vitamin D receptors in the development and treatment of human cancers. On-going research projects include the study of the functional interaction between PTEN tumor suppressor, FOXO factors and the androgen receptor in the growth and apoptosis of prostate cancer cells, the investigation of the role of the estrogen receptor in mediating the tissue-specific agonistic and antagonistic activity of Selective Estrogen Receptor Modulators (SERMs) in breast and endometrial cancer cells, and the study of the functions of vitamin D and its receptors in ovarian cancer development, treatment and prevention. Research activities in recent years also involve the study of the regulation of the FoxO factors and SIRT1 by interacting proteins and posttranslational modification such as ubiquitination and SUMOylation. The overall objective of the research is, through the elucidation of the mechanisms of steroid hormone and vitamin D actions in human cancer cells, to develop new hormonal intervention strategies for cancer patients or to improve patient’s response to existing hormonal or anti-hormonal treatments.

Current Courses

RefCourseSecCourse TitleCRDayTimeLocation
85876GMS 7930001Intro to Lab Med/Diagnosis
2T

9:00am-10:50am

CPH 2022