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Haitao "Mark" Ji

Haitao "Mark" Ji
Associate Professor


Office: MRC 4047
Phone: 813/745-8070



Ph.D. in Medicinal Chemistry, School of Pharmacy, Second Military Medical University, China 1999
Postdoc Fellow, Department of Chemistry, Northwestern University 2002-2006
Research Associate Professor, Department of Chemistry, Northwestern University 2006-2010


Dr. Ji’s research is Medicinal Chemistry and Chemical Biology. The lab’s efforts are mainly focused on the rational design, synthesis, and biological evaluation of drug-like small molecules that can modulate cellular signaling pathways with an emphasis on protein–protein interactions (PPIs) and target specificity. In general, the research in the Ji lab has two directions. One is the development of new tools/techniques to design potent and selective small-molecule inhibitors for the PPIs of interest. The second is the application of new tools to designing selective PPI inhibitors for clinically highly relevant signaling pathways and characterizing the biological activities of new inhibitors using biochemical and cell-based assays. Our goal is to use multidisciplinary approaches to tackle fundamental problems associated with human diseases, and translate the fundamental scientific findings into biomedical and biotechnological applications.

Graduate students in the Ji lab expect to receive training in rational drug design, synthetic organic chemistry, medicinal chemistry, chemical biology, and molecular and cell biology.