banner USF Home College of Arts & Sciences OASIS myUSF USF A-Z Index

USF Home > College of Arts and Sciences > Cancer Biology Ph.D. Program

Shengyu Yang
Assistant Professor


Phone: 813/745-8371


Institute of Biophysics, Chinese Academy of Sciences, Beijing, China(2001)
Post-Doctoral Fellow, Weill Medical College, Cornell University, NY (2002-2010)


The research efforts in our lab focus on the modulation of actin cytoskeleton in cancer metastasis. Metastasis is a multi-step process wherein cancer cells spread from a primary tumor to distant organs. One critical signature of metastatic cancer cells is enhanced migration and invasion, which are responsible for the infiltration of metastatic cells into lymphatic and blood vessels, as well as the extravasation of cancer cells into secondary organs. The driving forces of cell migration and invasion are conferred by the actin cytoskeleton and focal adhesions that anchor actin filaments to the extracellular matrix. Our long term goals are to reveal the actin cytoskeleton abnormalities that drive cancer metastasis and to develop anti-metastasis agents targeting actin cytoskeleton.