University of South Florida

Cancer Biology Ph.D. Program at the

Johnathan M. Lancaster, M.D. , Ph.D. Assistant Professor in the Department of Oncologic Sciences Division Chief, Gynecologic Oncology Program Medical Director, Lifetime Cancer Screening & Prevention Center Member-in-Residence of the Moffitt Cancer Center E-mail: Johnathan.Lancaster@moffitt.org Phone: (813)745-4734

Training
B. Sc.: University of Wales College of Medicine, 1991.
MB, B.Ch.: University of Wales College of Medicine, 1992.
M.D.: University of Wales College of Medicine, Molecular Genetics, 1997.
Ph.D.: University of Wales College of Medicine, Molecular Genetics, 2005
Fogarty Research Fellow: NIEHS, NIH, North Carolina, 1996.
Research Associate: Duke University Medical Center, Dept. of Surgery, 1997.
Resident: Duke University Medical Center, Obstetrics & Gynecology, 2000.
Fellow: Duke University Medical Center, Gynecologic Oncology, 2003.

Research Interests

Dr. Lancaster's active research program is investigating the molecular genetic etiology of ovarian cancer development, progression, and response to therapy. Translational applications of this research are anticipated to include microarray expression profile-directed chemotherapeutic interventions for primary and recurrent ovarian cancer.

Search for publications by:   
This search will be conducted at the US National Library of Medicine (NLM) and PubMed.

Selected Publications

A Bild, G Yao, J Chang, Q Wang, A Potti, D Chasse, M Joshi, D Harpole, JM Lancaster, A Berchuck, J Olson Jr, J Marks, H Dressman, M West, J Nevins.  Signatures of Oncogenic Pathway Deregulation in Human Cancers.  Nature, 19;439(7074):353-7, 2006

JM Lancaster, R Sayer, J Pittman, J Gray, R Whitaker, I Konidari, D Schomberg, J Marks, A Berchuck.  High expression of insulin-like growth factor binding protein-2 (IGFBP-2) in epithelial ovarian cancers produces elevated pre-operative serum levels. International Journal of Gynecological Cancer, 16:1529-1535, 2006

JM Lancaster, H Dressman, J Pittman, R Sayer, M Martino, J Cragun. A Henriott, J Gray, R Sutphen, A Elahi, R Whitaker, M West, J Marks, R Nevins, A Berchuck.  Identification of genes associated with ovarian cancer metastasis using microarray expression analysis.International Journal of Gynecological Cancer, 16:1733-1745, 2006

Anil Potti,  Holly K. Dressman, Andrea Bild, Richard F. Riedel, Gina Chan, Robyn Sayer, Janiel Cragun, Hope Cottrill, Michael J. Kelley,  Rebecca Petersen, David Harpole,  Jeffrey Marks, Andrew Berchuck, Geoffrey S. Ginsburg, Phillip Febbo,  JM Lancaster, and Joseph R. Nevins.  A Genomic Strategy to Guide Use of Chemotherapeutics in Solid Tumors.  Nature Medicine, 12(11):1294-300, 2006

HK Dressman, A Berchuck, G Chan, J Zhai, A Bild,  R Sayer, J Cragun, J Clarke, RS Whitaker, LiHua Li, Jonathan Gray, Jeffrey Marks, GS  Ginsburg, A Potti, M West, JR Nevins, JM Lancaster.  An Integrated Genomic-Based Approach to Personalized Treatment of Patients with Advanced-Stage Ovarian Cancer. Journal of Clinical Oncology Feb 10;25(5):517-25, 2007