University of South Florida

Cancer Biology Ph.D. Program at the

Melvyn S. Tockman, M.D., Ph.D.
Professor in the Department of Oncologic Sciences; Respiratory Division

Program Leader, Molecular Screening and Population Studies

Member-in-Residence of the Moffitt Cancer Center

E-mail: Melvyn.Tockman@moffitt.org
Phone: (813)745-1714

Research Interests
The Molecular Screening Program (MSP) has been established to conduct translational research into discovery of markers of neoplastic transformation and confirmation of these markers in specimens from human populations. A funded Biomarker Development Laboratory of the NCI Early Detection Research Network, MSP is conducting clinical trials of hnRNP A2/B1 protein expression and helical CT screening for the early detection of lung cancer. Markers of promoter methylation, loss of heterozygosity, Transforming Growth Factor beta Receptor gene and downstream elements of the TGF signaling pathway are also under study.

Search for publications by:   
This search will be conducted at the US National Library of Medicine (NLM) and PubMed.

Selected Publications
Tockman MS. Advances in sputum analysis for screening and early detection of lung cancer. Cancer Control. 7;19-24, 2000.

Kennedy TC, Proudfoot SP, Piantadosi S, Wu L, Saccomanno G, Petty TL, Tockman MS. Efficacy of two sputum collection techniques in patients with airflow obstruction. ACTA Cytologica. 43:630-36, 1999.

Tockman MS, Mulshine JL, Piantadosi S, Erozan YS, Gupta PK, Ruckdeschel JC, Taylor PR, Zhukov T, Zhou WH, Qiao YL, Yao SX, for the LCEDWG Investigators and the YTC Investigators. Prospective Detection of Preclinical Lung Cancer: Results from Two Studies of hnRNP Overexpression. Clin Cancer Res 1997; 3:2237-46.